In a visionary contribution to the Analytical Separation Scientist on the future of chromatography, Hilder and Shellie postulated in 2013 that the next wave of separation technology will be smaller, faster and smarter*. At that time, the PharmaFluidics team was working hard to prepare for the introduction of a revolutionary technology for liquid chromatography. One year later, seed investment funds were secured to realize a paradigm shift in LC column technology.
The idea to realize micro Pillar Array Columns (µPACTM) for liquid chromatography dates back to an initiative taken by prof. Gert Desmet. Intrigued by the effects of order and disorder in particulate based separation systems, the desire to translate his exhaustive theoretical modeling work into a practical device suddenly became very near when prof. Wim De Malsche and colleagues succeeded in overcoming the critical micromachining challenges for making astonishingly efficient microfluidic liquid chromatography separation devices.
The company was founded as a spin-off of the University of Brussels (VUB) in 2010. A decade of top-level academic research has given the company a head start in transforming the concept from academic proof-of-principle to a commercial product that fulfills unmet needs for the real-life user community. A strong IP position has been obtained, covering all aspects of innovation.
PharmaFluidics wants to bring liquid chromatography to a next level of efficiency in all aspects, by providing separation devices with an unprecedented resolution, in a format that enables extreme user-friendliness and robustness, and opens the way to further miniaturization and integration.
* Hilder and Shellie, Future Separations, The Analytical Scientist, Issue 3, 2013, p 24 – 31.