Yes. Our µPAC™ columns are semi-conductive (the columns contain a microchip), thus when high voltage is applied to the ESI emitter you must ground the µPAC™ column. This is achieved by connecting the outlet union of the µPAC™ column to a grounded point on your HPLC or mass spectrometer with the blue coiled Ground it! grounding cable.
Related questionsHow should I correctly ground a µPAC™ column?