Our µPAC™ columns are fabricated by etching from a crystalline silicon wafer following lithographic definition of a pillar array. This means the µPAC™ columns consist of one piece of solid material. The columns are completely symmetrical and do not contain any frits. So, you can easily backflush the column without the risk of moving or breaking particles from the separation bed. Consequently, our µPACᵀᴹ columns are less vulnerable to clogging. We have analysed a range of challenging samples that failed with conventional packed-bed columns. No significant change in column backpressure or separation performance was apparent. More information is provided in our technical note on column robustness.
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