Conventional HPLC columns are fabricated by stacking (packed beds) or depositing (monoliths) material into a capillary. The µPAC™ (micro pillar array column) technology from PharmaFluidics is unique because the design is based on precise micro-machining of the chromatographic separation beds into silicon wafers. This approach creates three crucial and unique characteristics for our µPAC™ columns: (i) perfectly-ordered free-standing pillars; (ii) high-permeability that results in a low backpressure; and (iii) a chromatographic bed with a solid backbone.
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Can I use the µPAC™ column in both directions?