Yes, you can use a liquid junction. You will, however, need to connect the outlet union of the µPACᵀᴹ column to the liquid junction with a 360 µm O.D./20 µm I.D. fused silica capillary. Here, you can find information on the part numbers required for the union. This configuration is commonly-adopted at our expert centres and the additional connection between the column and the mass spectrometer neither results in any issues nor leads to any negative effects on the chromatography.

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µPACᵀᴹ connectivity

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Can I apply high voltage directly to the metal union after the µPAC™ column?

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