This column offers:

Optimal separation performance

Obtain more than double the protein identifications than on a 40 cm packed bed column as demonstrated in this webinar.

Improved coverage

µPACᵀᴹ provides comprehensive coverage in single shot proteome analysis, nearing the mark of 10,000 identifications. Discover the results in our executive summary or webinar.

Extreme robustness

Each column has been manufactured by etching channels and pillar arrays out of a solid silicon wafer. The column is perfectly bidirectional and contains no particles or frits. This prevents blockages and retention time variation over multiple runs. Run your entire project on a single column.

Increased column to column reproducibility

Each column is manufactured using the same lithographic mask, making every column identical. Replace μPACᵀᴹs without retention time shifts. Obtain results over time and across laboratories, sufficiently consistent for big data analysis.

High flow rate flexibility

The column can be operated at moderate LC pump pressures up to 350 bar over a wide range of flow rates (100 – 1,000 nL/min).

RELATED APPLICATION NOTES

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Webinar

Webinar – Using Micro Pillar Array Columns in Clinical Proteomics Setup – A Novel Nanoflow LC–MS Approach

Watch this webinar to hear, Dr. Jeff Op de Beeck, the Application Development Manager of PharmaFluidics, explain the µPAC™ technology and Dr. Goran Mitulović, head …

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Publications

Executive Summary LCGC – A Novel Nanoflow LC-MS Approach for Bottom-up Proteomics Using Micro Pillar Array Columns

LCGC wrote an executive summary about our webinar, A Novel Nanoflow LC-MS Approach for Bottom-up Proteomics Using Micro Pillar Array Columns. Our Application Development Manager, …

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Technical notes

Technical note 4: μPAC™ column performance with peptide standards: Thermo Scientific™ Pierce™ retention time calibration mixture

μPAC™ column performance with peptide standards: Thermo Scientific™ Pierce™ retention time calibration mixture Peptide standards are critical in mass spectrometry based proteomics to ensure optimal …

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Webinar

Webinar – Expanding the Limits of Shotgun Proteomics Using Micro Pillar Array Columns and Data-Independant Acquisition (DIA) Methods

In this webinar, Dr. Jeff Op de Beeck, the application development manager of PharmaFluidics, will explain specific features of the micro-chip-based pillar array chromatography and …

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Publications

Perfecting Proteomics Separations

An innovative award-winning micro-chip chromatography ‘column’, µPACᵀᴹ promises high-resolution separations of complex biological samples. Prof Kris Gevaert and Dr Francis Impens, from Ghent University and …

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Publications

Executive Summary LCGC – Expanding the Limits of Shotgun Proteomics Using Micro-Pillar Array Columns and Data-Independent Acquisition Methods

LCGC wrote an executive summary about our webinar with Biognosys, Expanding the Limits of Shotgun Proteomics Using Micro-Pillar Array Columns and Data-Independent Acquisition Methods. Our …

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We're updating our column format!

To be able to keep up with demand, we’ve upscaled our production. In this process, we’ve switched to a longer and thinner casing format, allowing the columns to fit in a larger range of column ovens. The physical properties and chromatographic performance remain unchanged.