This column offers:

Optimal separation performance

Obtain more than double the protein identifications than on a 40 cm packed bed column as demonstrated in this webinar.

Improved coverage

µPACᵀᴹ provides comprehensive coverage in single shot proteome analysis, nearing the mark of 10,000 identifications. Discover the results in our executive summary or webinar.

Extreme robustness

Each column has been manufactured by etching channels and pillar arrays out of a solid silicon wafer. The column is perfectly bidirectional and contains no particles or frits. This prevents blockages and retention time variation over multiple runs. Run your entire project on a single column.

Increased column to column reproducibility

Each column is manufactured using the same lithographic mask, making every column identical. Replace μPACᵀᴹs without retention time shifts. Obtain results over time and across laboratories, sufficiently consistent for big data analysis.

High flow rate flexibility

The column can be operated at moderate LC pump pressures up to 350 bar over a wide range of flow rates (100 – 1,000 nL/min).

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Publications

Micro Pillar Array Column Technology Coupled to PASEF: A Sensitive Approach to Analyze Host Cell Proteins

Improve your detection of Host Cell Proteins (HCPs) in monoclonal antibody (mAb) preparations by implementing a workflow combination with 200cm µPAC™ C18 columns, parallel accumulation …

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Publications

Koen Sandra – Overcoming antibody analytical challenges using the µPAC™ column

Biopharmaceutical products, such as monoclonal antibodies, are on the rise! Biopharmaceuticals currently account for 25% of the total pharmaceutical market and monoclonal antibodies are the …

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Publications

Andrea Sinz – How to overcome challenges with XL-MS to study whole proteomes

In this exclusive interview, Prof. Dr. Andrea Sinz discusses the steps her group has taken to move from single protein studies to complex networks and …

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We're updating our column format!

To be able to keep up with demand, we’ve upscaled our production. In this process, we’ve switched to a longer and thinner casing format, allowing the columns to fit in a larger range of column ovens. The physical properties and chromatographic performance remain unchanged.